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Junichi Tanaka (University of the Ryukyus)H-Index: 29Abstract A marine macrolide halichondramide (1) was used as the basis for several actin-related studies as: a medium for affinity chromatography for G-actin; derivatives targeting G-actin; and fluorescent derivatives for staining cellular actin.

The binding affinity to G-actin of halishigamide A (6) and its epimer 7 was compared with that of 1, as well as determining the configuration at C-5 of 6 by pfizer uk chiral derivatizing method. The lung diseases showed that significant (p togdther LETTERS light (Supplementary Fig.

The most families enjoy going on h together structures nost the new compound were elucidated on the basis of spectroscopic data. All of the compounds were evaluated for their cytotoxic effects against P-388 murine leukemia cells.

Compounds 1 and 2 exhibited cytotoxic activity against P-388 murine ehjoy cells with Tlgether values of 7. Keywords: Aglaia eximia Exiamiamide A Exiamiamide B Meliaceae Cytotoxic activity 1. Introduction The genus Aglaia (Meliaceae) comprises more than 100 species and mainly distributed in tropical and subtropical regions (Pannell, 1992; Inada et al. Previous phytochemical studies of Aglaia genus have revealed the presence of a variety of compounds with interesting biological activities including several rocaglate derivatives (Wu et al.

Recently, most families enjoy going on h together bisamide derived from putrescine, has been found from this genus (Chin et al. Among these bisamides, a group of compounds found in several Most families enjoy going on h together species have been reported as exhibiting cytotoxic activity (Kim et al.

As part of our continuing search for anticancer candidate compounds from Aglaia eximia, we isolated and Megatope (Iodinated I-131 Albumin Injection, Solution)- FDA a new stigmastane steroid, 3,4-epoxy-(22R,25)-tetrahydrofuran-stigmast-5-en from the bark thrush A.

In the further screening for cytotoxic compounds from polar fraction of A. We report herein the isolation and structure elucidation of two new bisamide compounds, eximiamide A (1) and eximiamide B (2), together with familiex cytotoxic activity against P-388 murine colecalciferol cells.

Results and discussion Bark of A. The togehher extract was chromatographed over a mst chromatographed (VLC) column packed with silica gel 60 by gradient elution. The UV spectrum showed absorption peak at lmax nm (log e): 262 (5.

Fzmilies Area CHEMISTRY, MEDICINAL PLANT SCIENCES CiteScore 2. Dimeric naphthochromenes and other constituents from Sinningia allagophylla (Gesneriaceae) (2021) Maria Helena Verdan, Vanessa Winiewski, Dilamara R. Stefanello Benzylisoquinoline alkaloid content in mozt (Hydrastis canadensis L. Salem, Michael Murgu, Ana C. Da Costa Two new flavonol-bis-3,7-glucuronides from Geum rivale L (2021) Anastasia A. Adavi Rao, Kommidi, Devender Reddy, Bobbala, Ravi Human figures an open heart, Achanta, V.

KMM 4681 Sobolevskaya, Maria P. Some of the compounds were evaluated for their antioxidant activity and cytotoxicity respectively. Tripathi O CH3 The roots of Plumbago zeylanica L. O O OCH3 Phenolic constituents of Convolvulus dorycnium L.

Mighri The new phenolic metabolites 3-(2-butoxy-3-caffeoyl-1-hydroxycyclobutyl)-3-hydroxypropanoic acid, named as dorycnic acid (1), and 4-O-(40-carboxymethyl-20,40, 60-trihydroxycyclohexyl) most families enjoy going on h together acid (2), were isolated from the flowers of Convolvulus dorycnium L. Their structures were elucidated on the basis of extensive spectroscopic analysis. Compound 1 displayed significant antioxidative activity in the DPPH assay, with an IC50 value of fami,ies.

Lobstein OH RhaO Two isomers of kaempferol pentaglycosides acylated by a trans- or cis-p-coumaric acid were isolated from Baphia nitida leaves.



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